Publications

[ - 2000 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 ]

2011

1. Wang X, Peng W, Ren J, Hu Z, Xu Ji, Lou Z, Li X, Yin W, Shen X, Porta C, Walter T, Rowlands D, Wang J*, Stuart D*, Fry E*, and Rao Z*. A sensor/adaptor mechanism for enterovirus uncoating from structures of EV71. Nature Structural & Molecular Biology (in press)

2. Zheng B, Yang W, Zhao X, Wang Y, Lou Z, Rao Z, Feng Y.Crystal structure of hyperthermophilic Endo-β-1,4-glucanase: Implications for catalytic mechanism and thermostability. J Biol Chem. 2011 Nov 29.

3. Yan L, Ma Y, Sun Y, Gao J, Chen X, Liu J, Wang C, Lou Z, Rao Z. Structural basis for mechanochemical role of Arabidopsis thaliana dynamin-related protein in membrane fission. J Mol Cell Biol. 2011 Nov 22.

4. Zhang W, Fu S, Liu X, Zhao X, Zhang W, Peng W, Wu C, Li Y, Li X, Bartlam M, Zeng ZH, Zhan Q, Rao Z. Crystal structure of human Gadd45 reveals an active dimer. Protein Cell. 2011 Oct;2(10):814-26.

5. Yang W, Chen WY, Wang H, Ho JW, Huang JD, Woo PC, Lau SK, Yuen KY, Zhang Q, Zhou W, Bartlam M, Watt RM, Rao Z. Structural and functional insight into the mechanism of an alkaline exonuclease from Laribacter hongkongensis. Nucleic Acids Res. 2011 Dec 1;39(22):9803-9819.

6. Chen Y, Tan M, Xia M, Hao N, Zhang XC, Huang P, Jiang X, Li X, Rao Z. Crystallography of a Lewis-binding norovirus, elucidation of strain-specificity to the polymorphic human histo-blood group antigens. PLoS Pathog. 2011 Jul;7(7):e1002152.

7. Guo Y, Wang J, Niu G, Shui W, Sun Y, Zhou H, Zhang Y, Yang C, Lou Z, Rao Z. A structural view of the antibiotic degradation enzyme NDM-1 from a superbug. Protein Cell. 2011 May;2(5):384-94.

8. Yu J, Li X, Wang Y, Li B, Li H, Li Y, Zhou W, Zhang C, Wang Y, Rao Z, Bartlam M, Cao Y. PDlim2 selectively interacts with the PDZ binding motif of highly pathogenic avian H5N1 influenza A virus NS1. PLoS One. 2011;6(5):e19511.

9. Whitehouse CJ, Yang W, Yorke JA, Tufton HG, Ogilvie LC, Bell SG, Zhou W, Bartlam M, Rao Z, Wong LL. Structure, electronic properties and catalytic behaviour of an activity-enhancing CYP102A1 (P450(BM3)) variant. Dalton Trans. 2011 May 20.

10. Peng W, Xu J, Guan X, Sun Y, Zhang XC, Li X, Rao Z.Structural study of the Cdc25 domain from Ral-specific guanine-nucleotide exchange factor RalGPS1a. Protein Cell. 2011 Apr;2(4):308-19.

11. Lu K, Li P, Zhang M, Xing G, Li X, Zhou W, Bartlam M, Zhang L, Rao Z, He F. Pivotal role of the c2 domain of the smurf1 ubiquitin ligase in substrate selection. J Biol Chem. 2011 May 13;286(19):16861-70.

12. Rao Z. A strong start, a promising future. Protein Cell. 2011 Jan;2(1):1.

13. Shan S, Chen X, Liu T, Zhao H, Rao Z, Lou Z. Crystal structure of 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase (IspE) from Mycobacterium tuberculosis. FASEB J. 2011 May;25(5):1577-84.

14. Hou H, Wang F, Zhang W, Wang D, Li X, Bartlam M, Shen Y, Yao X, Rao Z* (2011). Structure-functional analyses of CRHSP-24 plasticity and dynamics in oxidative stress response. J Biol Chem. 2011 Mar 18;286(11):9623-35.

15. Ma M, Bell SG, Yang W, Hao Y, Rees NH, Bartlam M, Zhou W, Wong LL, Rao Z* (2011). Structural Analysis of CYP101C1 from Novosphingobium aromaticivorans DSM12444. Chembiochem. 2011 Jan 3;12(1):88-99.

2010

16. Whitehouse CJ, Yang W, Yorke JA, Rowlatt BC, Strong AJ, Blanford CF, Bell SG, Bartlam M, Wong LL, Rao Z (2010). Structural Basis for the Properties of Two Single-Site Proline Mutants of CYP102A1 (P450(BM3)). Chembiochem. 11(18):2549-56.

17. Yang W, Bell SG, Wang H, Zhou W, Bartlam M, Wong LL, Rao Z (2010). The structure of CYP101D2 unveils a potential path for substrate entry into the active site. Biochem J. 433(1):85-93

18. Rao Z (2010). Opening up the group II chaperonins. Structure. 18(10):1221-2.

19. Yang J, Gan Z, Lou Z, Tao N, Mi Q, Liang L, Sun Y, Guo Y, Huang X, Zou C, Rao Z, Meng Z, Zhang K (2010).Crystal structure and mutagenesis analysis of a chitinase CrChi1 from the nematophagous fungus Clonostachys rosea in complex with caffeine. Microbiology. 156(Pt 12):3566-74

20. Wang H, Morita M, Yang X, Suzuki T, Yang W, Wang J, Ito K, Wang Q, Zhao C, Bartlam M, Yamamoto T, Rao Z* (2010). Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity. EMBO J. 29(15):2566-76

21. Fu S, Tong X, Cai C, Zhao Y, Wu Y, Li Y, Xu J, Zhang XC, Xu L, Chen W & Rao Z* (2010) The structure of tumor endothelial marker 8 (TEM8) extracellular domain and implications for its receptor function for recognizing anthrax toxin. PLoS ONE 5(6):e11203

22. Yang W, Bell SG, Wang H, Zhou W, Hoskins N, Dale A, Bartlam, M*, Wong, LL* & Rao Z (2010). Molecular characterization of a class I P450 electron transfer system from Novosphingobium aromaticivorans DSM12. J Biol Chem 285(35):27372-84

23. Xue F, Sun Y, Yan L, Zhao C, Chen J, Bartlam M, Li X, Lou Z* & Rao Z (2010) The Crystal Structure of the PRRSV Nonstructural Protein Nsp1{beta} Reveals a Novel Metal-dependent Nuclease. J Virol 84(13):6461-71

24. Huang B, Wu H, Hao N, Blombach F, van der Oost J, Li X, Zhang XC* & Rao Z (2010) Functional study on GTP hydrolysis by the GTP binding protein from Sulfolobus solfataricus, a member of the HflX family. J Biochem 148(1):103-13.

25. Lou Z, Li M, Sun YN, Liu Y, Liu Z, Wu W, Rao Z*(2010).Crystal Structure of a secreted lipase from Gibberella zeae reveals a novel “double-lock” mechanism. Protein & Cell 8:760-770.

26. MaY, Tong X, Xu X, Li X, Lou Z, Rao Z*(2010). Structures of the N- and C-terminal domains of MHV-A59 nucleocapsid protein corroborate a conserved RNA-protein binding mechanism in coronavirus. Protein & Cell 7:688-697.

27. Wu Y, Lou Z, Miao Y, Yu Y, Dong H, Peng W, Bartlam M, Li X & Rao Z* (2010) Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth pandemic in China. Protein & Cell 5:491-500.

28. Wang L, Zhang W, Lu W, Zhang XC, Li X & Rao Z* (2010) Crystal structures of NAC domains of human nascent polypeptide-associated complex (NAC) and its NAC subunit. Protein & Cell 4:406-416.

29. Li S, Zhao Q, Zhang Y, Zhang Y, Bartlam M, Li X & Rao Z* (2010). New nsp8 isoform suggests mechanism for tuning viral RNA synthesis. Protein & Cell 2:198-204.

30. Xu L, Huang B, Du H, Zhang XC, Xu J, Li X & Rao Z* (2010). Crystal structure of cytotoxin protein suilysin from Streptococcus suis. Protein & Cell 1:96-105.

31. Rao Z (2010).Protein & Cell: a new scientific journal for the 21st century global life sciences community. Protein & Cell 1:1

32. Liao S, Tung ET, Zheng W, Chong K, Xu Y, Dai P, Guo Y, Bartlam M, Yuen KY & Rao Z.* (2010) Crystal structure of the Mp1p ligand binding domain 2 reveals its function as a fatty acid binding protein. J Biol Chem 285(12):9211-20.

33. Liang L, Meng Z, Ye F, Yang J, Liu S, Sun Y, Guo Y, Mi Q, Huang X, Zou C, Rao Z, Lou Z. & Zhang KQ (2010) The crystal structures of two cuticle-degrading proteases from nematophagous fungi and their contribution to infection against nematodes. FASEB J 24:1391-400

34. Bell SG, Xu F, Johnson EO, Forward IM, Bartlam M, Rao Z. & Wong, L. L. (2010). Protein recognition in ferredoxin-P450 electron transfer in the class I CYP199A2 system from Rhosopseudomonas palustris. J Biol Inorg Chem 15(3):315-28

35. Wu X, Ye S, Guo S, Yan W, Bartlam M. & Rao Z.* (2010). Structural basis for a reciprocating mechanism of negative cooperativity in dimeric phospagen kinase activity. FASEB J 24(1):242-52.

36. Wu H, Sun L, Blombach F, Brouns SJ, Snijders AP, Lorenzen K, van der Heuvel RH, Heck AJ, Fu S, Li X, Zhang XC, Rao Z. & van der Oost J. (2010) Structure of the ribosome associating GTPase HflX. Proteins 15:705-13.

37. Zhou X, Lou Z, Fu S, Yang A, Shen H, Li Z, Feng Y, Bartlam M, Wang H & Rao Z* (2010). Crystal structure of ArgP from Mycobacterium tuberculosis confirms two distinct conformations of full-length LysR transcriptional regulators and reveals its function in DNA binding and transcriptional regulation. J. Mol. Biol. 396:1012-24.

2009

38. Sun Y, Xue F, Guo Y, Ma M, Hao N, Zhang XC, Lou Z*, Li X* & Rao Z. (2009) Crystal Structure of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Leader Protease Nsp1{alpha} J Virol. 83:10931-40.

39. Xu F, Bell SG, Peng Y, Johnson EO, Bartlam M, Rao Z & Wong LL. 2009. Crystal structure of a ferredoxin reductase for the CYP199A2 system from Rhodopseudomonas palustris. Proteins. 77(4):867-80

40. Xu X, Lou Z, Ma Y, Chen X, Yang Z, Tong X, Zhao Q, Xu Y, Deng H, Bartlam M & Rao Z*. 2009. Crystal structure of the C-terminal cytoplasmic domain of non-structural protein 4 from mouse hepatitis virus A59. PLoS One. 2009 4(7):e6217

41. Guo S, Ye S, Liu Y, Wei L, Xue J, Wu H, Song F, Zhang J, Wu X, Huang D* & Rao Z*. 2009. Crystal structure of Bacillus thuringiensis Cry8Ea1: An insecticidal toxin toxic to underground pests, the larvae of Holotrichia parallela. J Struct Biol.168(2):259-66

42. Zhao C, Lou Z, Guo Y, Ma M, Chen Y, Liang S, Zhang L, Chen S, Li X, Liu Y*, Bartlam M & Rao Z*. 2009. Nucleoside monophosphate complex structures of the endonuclease domain from the influenza virus polymerase PA subunit reveal the substrate binding site inside the catalytic center. J Virol. 83(18):9024-30

43. Zhang W, Wang L, Liu Y, Xu J, Zhu G, Cang H, Li X, Bartlam M, Hensley K, Li G, Rao Z* & Zhang XC. 2009. Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione. Genes Dev. 23(12):1387-92

44. Wang X, Lou Z, Dong X, Yang W, Peng Y, Yin B, Gong Y, Yuan J, Zhou W, Bartlam M*, Peng X* & Rao Z. 2009. Crystal structure of the C-terminal domain of human DPY-30-like protein: A component of the histone methyltransferase complex. J Mol Biol. 390(3):530-7

45. Liu Y, Lou Z, Bartlam M & Rao Z. 2009. Structure-function studies of the influenza virus RNA polymerase PA subunit. Sci China C Life Sci. 52(5):450-8

46. Zhong N, Zhang S, Xue F, Kang X, Zou P, Chen J, Liang C, Rao Z, Jin C, Lou Z* & Xia B*. 2009. C-terminal domain of SARS-CoV main protease can form a 3D domain-swapped dimer. Protein Sci, 18(4):839-44.

47. Yuan P, Bartlam M, Lou Z, Chen S, Zhou J, He X, Lv Z, Ge R, Li X, Deng T, Fodor E, Rao Z* & Liu Y*. 2009. Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site. Nature, 458(7240):909-13

48. Meng Z*, Liu Z, Lou Z, Gong X, Cao Y, Bartlam M, Zhang K & Rao Z. 2009. Purification, Characterization and Crystallization of Pyrroline-5-carboxylate Reductase From the Hyperthermophilic Archaeon Sulfolobus Solfataricus. Prot. Exp. Purif., 64(2):125-130

49. Xu Y, Cong L, Chen C, Wei L, Zhao Q, Xu X, Ma Y, Bartlam M & Rao Z*. 2009. Crystal structures of two coronavirus ADP-ribose-1"-monophosphatases and their complexes with ADP-ribose: a systematic structural analysis of the viral ADRP domain. J. Virol., 83(2):1083-1092

50. Liu X, Xu L, Liu Y, Tong X, Zhu G, Zhang XC*, Li X* & Rao Z. 2009. Crystal structure of the hexamer of human heat shock factor binding protein 1. Proteins, 75(1):1-11

51. Lü Y, Yang H, Hu H, Wang Y, Rao Z & Jin C. 2009. Mutation of Trp137 to glutamate completely removes transglycosyl activity associated with the Aspergillus fumigatus AfChiB1. Glycoconj. J, 26(5):525-34

52. Kondo N, Ebihara A, Ru H, Kuramitsu S, Iwamoto A, Rao Z & Matsuda Z. 2009. Thermus thermophilus-derived protein tags that aid in preparation of insoluble viral proteins. Anal Biochem, 385(2):278-285

2008

53. He X, Zhou J, Bartlam M, Zhang R, Ma J, Lou Z, Li X, Li J, Joachimiak A., Zeng Z, Ge R, Rao Z* & Liu YF*. 2008. Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus Nature, 454(7208):1123-6.

54. Yang X, Morita M, Wang H, Suzuki T, Yang W, Lou Y, Zhao C, Yu Y, Bartlam M*, Yamamoto T* & Rao Z. 2008. Crystal structures of human BTG2 and mouse TIS21 involved in suppression of CAF1 deadenylase activity. Nucleic Acids Research，36(21):6872-6881

55. Yang Y, Wu F, Ward T, Yan F, Wu Q, Wang Z, McGlothen T, Peng W, You T, Sun M, Cui T, Hu R, Dou Z, Zhu J, Xie W, Rao Z, Ding X & Yao X. 2008. Phosphorylation of HsMis13 by aurora B is essential for assembly of functional kinetochore. J. Biol. Chem. 283(39):26726-26736

56. Li X, Lou Z, Li X, Zhou W, Ma M, Cao Y*, Geng Y, Bartlam M, Zhang XC* & Rao Z. 2008. Structure of human cytosolic X-prolyl aminopeptidase: a double Mn(II) dependent dimeric enzyme with a novel three-domain subunit. J Biol Chem, 283(33):22858-22866

57. Zhang R, Zhu G, Zhang W, Cao S, Ou X, Li X, Bartlam M, Xu Y*, Zhang XC* & Rao Z. 2008. Crystal structure of a carbonyl reductase from Candida Parapsilosis with anti-prelog stereo specificity. Protein Science. 17: 1412-1423

58. Chen J, Li W, Wang M, Zhu G, Liu D, Sun F, Hao N, Li XM, Rao Z & Zhang XC*. 2008. Crystal Structure and Mutagenic Analysis of GDOsp, a Gentisate 1,2- Dioxygenase from Silicibacter Pomeroyi. Protein Science. 17: 1362-1373

59. Gräslund S, Nordlund P, Weigelt J, Bray J, Gileadi O, Knapp S, Oppermann U, Arrowsmith C, Hui R, Ming J, dhe-Paganon S, Park HW, Savchenko A, Yee A, Edwards A, Vincentelli R, Cambillau C, Kim R, Kim SH, Rao Z, Shi Y, Terwilliger TC, Kim CY, Hung LW, Waldo GS, Peleg Y, Albeck S, Unger T, Dym O, Prilusky J, Sussman JL, Stevens RC, Lesley SA, Wilson IA, Joachimiak A, Collart F, Dementieva I, Donnelly MI, Eschenfeldt WH, Kim Y, Stols L, Wu R, Zhou M, Burley SK, Emtage JS, Sauder JM, Thompson D, Bain K, Luz J, Gheyi T, Zhang F, Atwell S, Almo SC, Bonanno JB, Fiser A, Swaminathan S, Studier FW, Chance MR, Sali A, Acton TB, Xiao R, Zhao L, Ma LC, Hunt JF, Tong L, Cunningham K, Inouye M, Anderson S, Janjua H, Shastry R, Ho CK, Wang D, Wang H, Jiang M, Montelione GT, Stuart DI, Owens RJ, Daenke S, Schütz A, Heinemann U, Yokoyama S, Büssow K, Gunsalus KC. 2008. Structural Genomics Consortium; China Structural Genomics Consortium; Northeast Structural Genomics Consortium, Protein production and purification. Nat Methods 5(2):135-146

60. Li L, Liu X, Yang W, Xu F, Feng L, Bartlam M*, Wang L*& Rao Z. 2008. Crystal structure of long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN: unveiling the long-chain alkane hydroxylase. J Mol Biol., 376(2): 453-465

61. Dong H, Li X, Lou Z, Xu X, Su D, Zhou X, Zhou W, Bartlam M* & Rao Z. 2008. Crystal structure and biochemical characterization of recombinant human calcyphosine delineates a novel EF-hand-containing protein family. J Mol Biol 383(3):455-464

62. Bell SG, Xu F, Forward I, Bartlam M, Rao Z & Wong LL*. 2008. Crystal Structure of CYP199A2, a Para-Substituted Benzoic Acid Oxidizing Cytochrome P450 from Rhodopseudomonas palustris. J Mol Biol 383:561–574

63. Zhao Q, Li S, Xue F, Zou Y, Chen C, Bartlam M & Rao Z*. 2008. Structure of the main protease from a global infectious coronavirus, HCoV-HKU1. J Virol 82: 8647-8655

64. Xue X, Yu H, Yang H, Xue F, Wu Z, Shen W, Li J, Zhou Z, Ding Y, Zhao Q, Zhang XC, Liao M, Bartlam M & Rao Z*. 2008. Structures of Two Coronavirus Main Proteases: Implications for Substrate Binding and Anti-viral Drug Design. J Virol, 82(5):2515-2527

65. Tan M, Xia M, Cao S, Huang P, Farkas T, Meller J, Hegde RS, Li X, Rao Z & Jiang X*. 2008. Elucidation of strain-specific interaction of a GII-4 norovirus with HBGA receptors by site-directed mutagenesis study. Virology, 379(2):324-334

66. Li M, Li S, Lou Z, Liao X, Zhao X, Meng Z, Bartlam M & Rao Z*. 2008. Crystal structure of human transgelin. J Struct Biol, 162: 229-236

67. Bartlam M, Xue X & Rao Z*. 2008. The search for a structural basis for therapeutic intervention against the SARS coronavirus. Acta Crystallogr A., 64(Pt 1): 204-213

68. Zhang R, Xu Y, Sun Y, Nie Y, Mu X, Li X, Zhang XC & Rao Z*. 2008. Crystallization and preliminary X-ray crystallographic analysis of a carbonyl reductase from Candida parapsilosis. Acta Crystallogr Sect F, 64(4): 252-254

69. Wei L, Chen C, Zhao Q, Li C, Cong L, Xu X, Ma Y, Liao M, Xu Y & Rao Z*. 2008. Purification, crystallization and preliminary crystallographic analysis of avian infectious bronchitis virus nsp3 ADRP domain. Acta Crystallogr Sect F, 64( 9):802-804

70. Zhang W, Zhao M, Li J, Li X, Zeng Z, Rao Z. 2008. Purification, crystallization and preliminary X-ray diffraction analysis of human Gadd45gamma. Acta Crystallogr F, 64(Pt 11):1070-1073

2007

71. Shaw N, Zhao M, Cheng C, Xu H, Saarikettu J, Li Y, Da Y, Yao Z, Silvennoinen O, Yang J*, Liu ZJ*, Wang BC & Rao Z. 2007. The multifunctional human p100 protein 'hooks' methylated ligands. Nat Struct Mol Biol. 14(8):779-784

72. Zhao Q, Qin L, Jiang F, Wu B, Yue W, Xu F, Rong Z, Yuan H, Xie X, Gao Y, Bai C, Bartlam M, Pei X* & Rao Z*. 2007. Structure of human spindlin1: tandem tudor-like domains for cell cycle regulation. J Biol Chem, 282(1):647-656

73. Ye S, Wu X, Wei L, Tang D, Sun P, Bartlam M & Rao Z*. 2007. An insight into the mechanism of human cysteine dioxygenase: Key roles of the thioether-bonded tyrosine-cysteine cofactor. J Biol Chem., 282(5):3391-3402

74. Yang X, Zhou J, Sun L, Wei Z, Gao J, Gong W, Xu RM, Rao Z & Liu Y*. 2007. Structural basis for the function of DCN-1 in protein Neddylation. J Biol Chem, 282(34): 24490-24494

75. Xue X, Yang H, Shen W, Zhao Q, Li J, Yang K, Chen C, Jin Y, Bartlam M & Rao Z*. 2007. Production of Authentic SARS-CoV Mpro with Enhanced Activity: Application as a Novel Tag-cleavage Endopeptidase for Protein Overproduction. J Mol Biol 366(3):965-975

76. Zheng W, Sun F, Bartlam M, Li XM, Li R & Rao Z*. 2007. The crystal structure of human isopentenyl diphosphate isomerase at 1.7 E resolution reveals its catalytic mechanism in isoprenoid biosynthesis. J Mol Biol 366(5):1447-1458

77. Wu B, Liu Y, Zhao Q, Liao S, Zhang J, Bartlam M, Chen W & Rao Z*. 2007. Crystal Structure of RS21-C6, Involved in Nucleoside Triphosphate Pyrophosphohydrolysis. J Mol Biol. 367(5):1405-1412

78. Li Z, Huang Y, Ge J, Fan H, Zhou X, Li S, Bartlam M, Wang H & Rao Z*. 2007. The Crystal Structure of MCAT from Mycobacterium tuberculosis Reveals Three New Catalytic Models. J Mol Biol. 371(4): 1075-1083

79. Cao S, Lou Z, Tan M, Chen Y, Liu Y, Zhang Z, Zhang XC, Jiang X, Li X & Rao Z*. 2007. Structural Basis for the Recognition of Blood Group Trisaccharides by Norovirus. J Virol. 81(11):5949-5957

80. Rao Z. 2007. History of protein crystallography in China. Philos Trans R Soc Lond B Biol Sci, 362(1482):1035-1042 （Review）

81. Bartlam M, Xu YY & Rao Z*. 2007. Structural proteomics of the SARS coronavirus: a model response to emerging infectious diseases. J Struct Funct Genomics. 8(2-3): 85-97 （Review）

82. Huo X, Su D, Wang AJ, Zhai YJ, Xu JX, Li X, Bartlam M*, Sun F* & Rao Z. 2007. Preliminary molecular characteristic and crystallization of mitochondrial respiratory Complex II from porcine heart. FEBS Journal, 274(6):1524-1529

83. Pang X, Xu F*, Bell SG, Guo D, Wong LL* & Rao Z. 2007. Purification, crystallization and preliminary crystallographic analysis of cytochrome P450 203A1 from Rhodopseudomonas palustris. Acta Cryst. Sect F 63(4):342-345

84. Peng Y, Xu F*, Bell SG, Wong LL* & Rao Z. 2007. Crystallization and preliminary X-ray diffraction studies of a ferredoxin reductase from Rhodopseudomonas palustris CGA009. Acta Crys. Sect F, 63(5): 422-425

85. Shaw N, Cheng C, Tempel W, Chang J, Ng J, Wang XY, Perrett S, Rose J, Rao Z, Wang BC & Liu ZJ*. 2007. (NZ)CH...O Contacts Assist Crystallization of a ParB-like Nuclease. BMC Struct Biol. 7: 46

86. Chu FL, Lou Z, Chen YW, Liu YW, Gao B, Zong LL, Khan A.H., Bell J.I., Rao Z & Gao F*. 2007. First glimpse of the peptide presentation by rhesus macaque MHC class I: crystal structures of Mamu-A*01 complexed with two immunogenic SIV epitopes and insights into CTL escape. J Immunol., 178(2): 944-952

87. Xu F, Bell SG, Rao Z* & Wong LL*. 2007. Structure-activity correlations in pentachlorobenzene oxidation by engineered cytochrome P450cam. Protein Eng Des Sel., 20(10): 473-80

88. Shaw N, Tempel W, Chang J, Yang H, Cheng C, Ng J, Rose J, Rao Z, Wang BC & Liu ZJ*. 2007. Crystal structure solution of a ParB-like nuclease at atomic resolution. Proteins. 70(1): 263-267

89. Zhu G, Chen J, Liu J, Brunzelle JS, Huang B, Wakeham N, Terzyan S, Li X, Rao Z, Li G, Zhang XC*. 2007. Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5. EMBO J. 26(14): 3484-3493

2006

90. Liu Z, Lin H, Ye S, Liu Q, Meng Z, Zhang C, Xia Y, Margoliash E* & Rao Z* & Liu X*. 2006. Remarkably high activities of testicular cytochrome c in destroying reactive oxygen species and in triggering apoptosis. Proc. Natl. Acad. Sci. USA，103(24): 8965-8970

91. Dong X, Xu F, Gong Y, Gao J, Lin P, Chen T, Pen Y, Qiang B, Yuan J, Peng X & Rao Z*. 2006. Crystal structure of the V domain of human Nectin-like molecule-1/SynCAM3/TSLL1/IGSF4B, a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule. J Biol Chem., 281(15):10610-10617

92. Li X, Chen Y, Liu Y, Gao J, Gao F, Bartlam M, Wu JY & Rao Z*. 2006. Structural basis of Robo proline-rich motif recognition by the srGAP1 Src homology 3 domain in the Slit-Robo signaling pathway. J Biol Chem. 281(38): 28430-28437

93. Meng Z, Lou Z, Liu Z, Li M, Zhao X, Bartlam M & Rao Z*. 2006. Crystal Structure of Human Pyrroline-5-carboxylate Reductase. J Mol Biol 359(5):1364-1377

94. Ou X, Ji C, Han X, Zhao X, Li X, Mao Y, Wong LL, Bartlam M & Rao Z*. 2006. Crystal Structures of Human Glycerol 3-phosphate Dehydrogenase 1 (GPD1). J Mol Biol., 357(3):858-869

95. Su, D, Lou Z, Sun F, Zhai Y, Yang H, Zhang R, Joachimiak A, Zhang XC, Bartlam M & Rao Z*. 2006. The dodecamer structure of the SARS coronavirus non-structural protein nsp10. J. Virol., 80(16):7902-7908

96. Xu, X, Zhai Y, Sun F, Lou Z, Su D, Xu Y, Zhang R, Joachimiak A, Zhang XC, Bartlam M & Rao Z*. 2006. A new anti-viral target revealed by the hexameric structure of the MHV coronavirus non-structural protein nsp15. J Virol, 80(16): 7909-7917

97. Yang H, Bartlam, M & Rao Z*. 2006. Drug Design Targeting the Main Protease, the Achilles’ Heel of Coronaviruses. Curr. Pharm. Design. 12(35):4573-4590 （Review）

98. Rao Z. Combating SARS in China: Experiences and Efforts to Coordinate Future Prevention. In: Anna Lindh Programme on Conflict Prevention: Health and Conflict Prevention (Mellbourn A., ed.) Gidlunds Hedemora/Sweden, 105-118

99. Meng Z, Lou Z, Liu Z, Dong H, Bartlam M & Rao Z*. 2006. Purification, characterization and crystallization of human pyrroline-5-carboxylate reductase. Protein Expr Purif. 49(1): 83-87

100. Li X, Liu X, Sun F, Gao J, Zhou H, Gao GF, Bartlam M & Rao Z*. 2006. Crystal structure of the N-terminal SH3 domain of mouse betaPIX, p21-activated kinase-interacting exchange factor. Biochem Biophys Res Commun, 339(1):407-414

101. Lou Z, Xu Y, Xiang K, Su N, Qin L, Li X, Gao GF, Bartlam M, & Rao Z*. 2006. Crystal structures of Nipah and Hendra virus fusion core proteins. FEBS J., 273(19):4538-4547

102. Jiang F, Zhao Q, Qin L, Pang H, Pei X & Rao Z*. 2006. Expression, purification, crystallization and preliminary X-ray analysis of human spindlin1, an ovarian cancer-related protein. Protein & Peptide Letters, 13: 203-205

103. Chu LH, Choy WY, Tsai SN, Rao Z & Ngai SM*. 2006. Rapid peptide-based screening on the substrate specificity of severe acute respiratory syndrome (SARS) coronavirus 3C-like protease by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Protein Science, 15(4):699-709

104. Liu Y, Xu Y, Lou Z, Zhu J, Hu X, Gao GF, Qiu B, Rao Z & Tien P*. 2006. Structural characterization of mumps virus fusion protein core. Biochem Biophys Res Commun. 348(3): 916-922

105. Bell SG, Hoskins N, Xu F, Caprotti D, Rao Z & Wong LL*. 2006. Cytochrome P450 enzymes from the metabolically diverse bacterium Rhodopseudomonas palustris. Biochem Biophys Res Commun, 342(1): 191-196

106. Hilgenfeld R, Anand K, Mesters JR, Rao Z, Shen X, Jiang H, Tan J & Verschueren KH. 2006. Structure and dynamics of SARS coronavirus main proteinase (Mpro). Adv Exp Med Biol., 581: 585-591

107. Kannan S, Pang H, Foster DC, Rao Z & Wu M*. 2006. Human 8-oxoguanine DNA glycosylase increases resistance to hyperoxic cytotoxicity in lung epithelial cells and involvement with altered MAPK activity. Cell Death Differ，13(2):311-323

2005

108. Sun F, Huo X, Zhai YJ, Wang AJ, Xu JX, Su D, Bartlam M & Rao Z*. 2005. Crystal Structure of Mitochondrial Respiratory Membrane Protein Complex Ⅱ. Cell, 121: 1043-1057

109. Yang H, Xie WQ, Xue XY, Yang KL, Ma J, Liang WX, Zhao Q, Zhou Z, Pei DQ, J. Ziebuhr, R. Hilgenfeld, K. Y. Yuen, Wong L., Gao GX, Chen SJ, Chen Z, Ma DW, Bartlam M & Rao Z*. 2005. Design of Wide-Spectrum Inhibitors Targeting Coronavirus Main Proteases. PLoS Biology, 3(10):e324, 1742-1752

110. Zhai Y, Sun F, Li X, Pang H, Xu X, Bartlam M, & Rao Z*. 2005. Structural insights into coronavirus transcription/replication from the crystal structure of the SARS-CoV hexadecameric nsp7•nsp8 super-complex. Nature Structural & Molecular Biology, 12(11): 980-986

111. Bartlam M, Yang H & Rao Z*. 2005. Structural insights into SARS coronavirus proteins. Current Opinion in Structural Biology, 15:

664-672 （Review）

112. Xu F, Bell SG, Lednik J, Insley A, Rao Z* & Wong L*. 2005. The Heme Monooxygenase Cytochrome P450cam Can Be Engineered to Oxidize Ethane to Ethanol. Angew Chem Int Ed Engl., 44(26):4029-4032

113. Rao Z. 2005. YjjX: From Structure “Tu” Function. Structure, 13(10):1401-1402 (Preview)

114. Wang H; Pang H; Bartlam M & Rao Z*. 2005. Crystal structure of human E1 enzyme and its complex with a substrate analog reveals the mechanism of its phosphatase / enolase activity. J Mol Biol., 348(4): 917-926

115. Dong YJ, Bartlam M, Sun L, Zhou YF, Zhang ZP, Zhang CG, Rao Z* & Zhang XE*. 2005. Crystal structure of methyl parathion hydrolase from Pseudomonas sp WBC-3. J Mol Biol., 353(3):655-663

116. Sun P, Ye S, S. Ferrandon, T.C. Evans, Xu MQ & Rao Z*. 2005. Crystal structures of an intein from the split dnaE gene of Synechocystis sp. PCC6803 reveal the catalytic model without the penultimate histidine and the mechanism of zinc ion inhibition of protein splicing. J Mol Biol., 353(5): 1093-1105

117. Tan J, Verschueren KH, Anand K, Shen J, Yang M, Xu Y, Rao Z, Bigalke J, Heisen B, Mesters JR, Chen K, Shen X, Jiang H, Hilgenfeld R. 2005. pH-dependent Conformational Flexibility of the SARS-CoV Main Proteinase (M(pro)) Dimer: Molecular Dynamics Simulations and Multiple X-ray Structure Analyses. J Mol Biol., 354(1): 25-40

118. Lou, Z, Hou J, Liang X, Chen JS, Qiu P, Liu Y, Li M, Rao Z* & Yan GM. 2005. Crystal structure of a non-hemorrhagic fibrin(ogen)olytic metalloproteinase complexed with a novel natural tri-peptide inhibitor from venom of Agkistrodon acutus. Journal of Structural Biology, 152(3):195-203

119. Tsiftsoglou SA, Willis AC, Li P, Chen X, Mitchell DA, Rao Z & Sim RB. 2005. The Catalytically Active Serine Protease Domain of Human Complement Factor I. Biochemistry, 44(16): 6239-6249

120. Sun L, M Bartlam, Liu Y, Pang H & Rao Z*. 2005. Crystal structure of the pyridoxal-5'-phosphate-dependent serine dehydratase from human liver. Protein Science, 14(3): 791-798

121. Dong XH, Peng Y, Peng Y, Xu F, He XJ, Wang F, Peng XZ, Qiang BQ, Yuan JG & Rao Z*. 2005. Characterization and crystallization of human DPY-30-like protein, an essential component of dosage compensation complex. Biochim Biophys Acta., 1753(2):257-262

122. Anand K., Yang H., Bartlam M., Rao Z. & Hilgenfeld R. 2005. Coronavirus main proteinase: target for antiviral drug therapy". In: Coronaviruses with Special Emphasis on First Insights Concerning SARS (Schmidt, A., Wolff, M.H., Weber, O., eds.). Birkhäuser Verlag Basel/Switzerland, pp. 173-199

123. Zhao X, Li M, Xu Y & Rao Z*. 2005. Cloning, expression, purification, crystallization and preliminary crystallographic study of the protein module (BIV2-Helix) in the fusion core of bovine immunodeficiency-like virus (BIV) gp40. Acta Cryst. F, 61(2): 249-251

124. Wang H, Pang H, Ding Y, Li Y, Wu X & Rao Z*. 2005. Purification, crystallization and preliminary X-ray diffraction analysis of human enolase-phosphatase E1. Acta Cryst. F,61(5): 521–523

125. Sun Y, Li X, Wu B, Sun P & Rao Z*. 2005. Crystallization and preliminary crystallographic analysis of human eukaryotic translation initiation factor 5A (eIF-5A). Protein & Peptide Letters, 12(7): 713-715

126. He X, Li L, Hou H, Zhao Y, Liang A & Rao Z*. 2005. Preliminary X-ray crystallographic analysis of centrin from ciliate Euplotes octocarinatus. Protein & Peptide Letters, 12(6): 609-611

127. Zhang H, Zheng B, Peng Y, Lou Z, Feng Y & Rao Z*. 2005. Expression, Purification and Crystal Structure of a Truncated Acylpeptide Hydrolase from Aeropyrum pernix K1. Acta Biochim Biophys Sin, 37(9): 613-617

128. Liu Y, Xu Y, Zhu J, Qiu B, Rao Z, Gao GF, Tien P. 2005. Crystallization and preliminary X-ray diffraction analysis of central structure domains from mumps virus F protein. Acta Cryst Sect F, 61(9): 855-857

129. Chu F, Lou Z, Gao B, Bell JI, Rao Z & Gao GF*. 2005. Complex assembly, crystallization and preliminary X-ray crystallographic studies of rhesus macaque MHC Mamu-A*01 complexed with an immunodominant SIV-Gag nonapeptide. Acta Cryst Sect F, 61(6): 614-616

130. Yuan F, Lou Z, Li X, Chen YW, Bell JI, Rao Z & Gao GF*. 2005. Refolding, crystallization and preliminary X-ray structural studies of the West Nile virus envelope (E) protein domain III. Acta Cryst Sect F, 61(4): 421-423

131. Hou J, Li M, Chen J, Qiu P, Liang X, Lou Z, Rao Z & Yan G*. 2005. Crystallization and preliminary X-ray studies of a non-haemorrhagic fibrin(ogen)olytic metalloproteinase from the venom of Agkistrodon acutus. Acta Cryst Sect F, 61(4): 355-358

132. Li M, Meng ZH, Xu Y, Lou Z & Rao Z*. 2005. Crystallization and preliminary X-ray crystallographic analysis of osteoclast-stimulating factor. Acta Cryst Section F, 61(1): 128-130

2004

133. Wang X, Xu Y, Cole DK, Lou Z, Liu Y, Rao Z, Wang M & Gao GF*. 2004. Biochemical, biophysical and preliminary X-ray crystallographic analyses of the fusion core of Sendai virus F protein. Acta Cryst D, 60(9): 1632-1635

134. Wu B, Li P, Liu Y, Lou Z, Ding Y, Shu C, Ye S, Bartlam M, Shen B* & Rao Z*. 2004. 3D structure of human FK506-binding protein 52: implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex. Proc Natl Acad Sci USA., 101(22): 8348-8353

135. Bartlam M, Wang G, Yang H, Gao R, Zhao X, Xie G, Cao S, Feng Y & Rao Z*. 2004. Crystal Structure of an Acylpeptide Hydrolase/Esterase from Aeropyrum pernix K1. Structure, 12(8):1481-1488

136. Pang H, Bartlam M, Zeng Q, Miyatake H, Hisano T, Miki K, Wong LL, Gao GF & Rao Z*. 2004. Crystal Structure of Human Pirin: AN IRON-BINDING NUCLEAR PROTEIN AND TRANSCRIPTION COFACTOR. J Biol Chem., 279(2): 1491-1498

137. Shi N, Ye S, Bartlam M, Yang M, Wu J, Liu Y, Sun F, Han X, Peng X, Qiang B, Yuan J*& Rao Z*. 2004. Structural Basis for the Specific Recognition of RET by the Dok1 Phosphotyrosine Binding Domain. J Biol Chem., 279(6): 4962-4969

138. Xu Y, Liu Y, Lou Z, Qin L, Bai Z, Pang H, Tien P, Gao G* & Rao Z*. 2004. Structural basis for coronavirus-mediated membrane fusion: Crystal structure of mouse hepatitis virus spike protein fusion core. J Biol Chem., 279 (29): 30514-30522

139. Xu Y, Lou Z, Liu Y, Pang H, Tien P, Gao G.F & Rao Z*. 2004. Crystal structure of Severe Acute Respiratory Syndrome Coronavirus Spike Protein Fusion Core*. J Biol Chem., 279(47): 49414-49419

140. Xu Y, Zhu J, Liu Y, Lou Z, Yuan F, Liu Y, Cole D K, Ni L, Su N, Qin L, Li X, Bai Z, Bell J I, Pang H, Tien P, Gao G F & Rao Z*. 2004. Characterization of the heptad repeat regions, HR1 and HR2, and design of a fusion core structure model of the spike protein from severe acute respiratory syndrome (SARS) coronavirus. Biochemistry (US) 43(44): 14064-14071

141. Wang G*, Zhang S, Ferning DG, Spiller D, Martin-Fernandez M, Zhang H, Ding Y, Rao Z, Rudland P, Barraclough R. 2004. Heterodimerisation and the heterodimeric interfaces of S100A1 and S100P, Biochem J., 382(1): 375-383

142. Liu B, Bartlam M, Gao R, Zhou W, Pang H, Liu Y & Rao Z*. 2004. Crystal Structure of the Hyperthermophilic Inorganic Pyrophosphatase from the Archaeon Pyrococcus horikoshii. Biophys J., 86(1): 420-427

143. Li X, Liu X, Lou Z, Duan X, Wu H, Liu Y* & Rao Z*. 2004. Crystal Structure of Human Coactosin-like Protein at 1.9 Å Resolution. Protein Science, 13(11): 2845-2851

144. Pang H, Liu Y, Han X, Xu Y, Jiang F, Wu D, Kong X, Bartlam M, & Rao Z*. 2004. Protective humoral responses to severe acute respiratory syndrome-associated coronavirus: implications for the design of an effective protein-based vaccine, J Gen Virol, 85: 3109-3113

145. Xu Y, Lou Z, Liu Y, Cole DK, Su N, Qin L, Li X, Bai Z, Rao Z* & Gao GF*. 2004. Crystallization and preliminary crystallographic analysis of the fusion core from two new zoonotic paramyxoviruses, Nipah virus and Hendra virus. Acta Cryst., D60(6): 1161-1164

146. Shi N, Ni M, Yang M, Wu J, Peng Y, Gao F, Sun F, Peng X, Qiang B, Rao Z* & Yuan J*. 2004. Expression, crystallization and preliminary X-ray studies of the recombinant PTB domain of mouse dok-1 protein. Acta Cryst., D60(2): 334-336

147. Liu B, Li X, Gao R, Zhou W, Xie G, Bartlam M, Pang H, Feng Y & Rao Z*. 2004. Crystallization and preliminary X-ray analysis of inorganic pyrophosphatase from the hyperthermophilic archaeon Pyrococcus horikoshii OT3. Acta Cryst., D 60(3): 577-579

148. Sun L, Dong Y, Zhou Y, Yang M, Zhang C, Rao Z & Zhang XE*. 2004. Crystallization and preliminary X-ray studies of methyl parathion hydrolase from Pseudomonas sp. WBC-3. Acta Cryst., D 60(5): 954-956

149. Hu H, Wang G, Yang H, Zhou J, Mo L, Jin CS, Jin C* & Rao Z*. 2004. Crystallization and preliminary crystallographic analysis of a native chitinase from the fungal pathogen Aspergillus fumigatus YJ-407 (afCHI). Acta Cryst., D60 939-940

150. Zhou M, Xu Y, Lou Z, Cole DK, Li X, Liu Y, Tien P, Rao Z & Gao GF*. 2004. Complex assembly, crystallization and preliminary X-ray crystallographic studies of MHC H-2K(d) complexed with an HBV-core nonapeptide. Acta Cryst., D 60(8): 1473-1475

151. Xu Y, Bai Z, Qin L, Li X, Gao GF* & Rao Z*. 2004. Crystallization and Preliminary Crystallographic analysis of fusion core of spike protein of the murine coronavirus mouse hepatitis virus (MHV). Acta Cryst., D60(11):2013-2015 (times cited: 2)

152. Xu Y, Su N, Qin L, Bai ZH, Gao GF* & Rao Z*. 2004. Crystallization and preliminary crystallographic analysis of heptad repeat complex of SARS coronavirus spike protein. Acta Cryst., D60(12): 2377-2379

153. Li X, Liu XQ, Zhao Q, Liu Y, Duan X & Rao Z*. 2004. Crystallization and preliminary crystallographic studies of human coactosin-like protein (CLP). Acta Cryst., D60(12): 2387-2388

154. Xu Y, Gao S, Cole DK, Zhu J, Su N, Wang H, Gao GF* & Rao Z*. 2004. Basis for fusion inhibition by peptides: analysis of the heptad repeat regions of the fusion proteins from Nipah and Hendra viruses, newly emergent zoonotic paramyxoviruses. Biochem Biophys Res Commun, 315(3):664-670

155. Zhu J, Xiao G, Xu Y, Yuan F, Zheng C, Liu Y, Yan H, Cole DK, Bell JI, Rao Z, Tien P & Gao GF*. 2004. Following the rule: formation of the 6-helix bundle of the fusion core from severe acute respiratory syndrome coronavirus spike protein and identification of potent peptide inhibitors. Biochem Biophys Res Commun, 319(1):283-288

156. Han X, Bartlam M, Jin YH, Liu X, He X, Cai X, Xie Q & Rao Z*. 2004. The expression of SARS-CoV M gene in P. Pastoris and the diagnostic utility of the expression product. J Virol Methods, 122(1):105-111

157. Xu Y, Cole D.K, Lou Z, Liu Y, Qin L, Li X, Bai Z, Yuan F, Rao Z* & Gao G.F *. 2004. Construct design, biophysical and biochemical characterization of the fusion core from mouse hepatitis virus (a coronavirus) spike protein. Protein expression and purification, 38(1):116-122

2003

158. Yang H, Yang M, Ding Y, Liu Y, Lou Z, Sun L, Zhou Z, Ye S, Pang H, Gao G, Anand K, Bartlam M, Hilgenfeld R & Rao Z*. 2003. The Crystal Structures of SARS Virus Main Protease Mpro and Its Complex with an Inhibitor. Proc Natl Acad Sci USA., 100(23): 13190-13195

159. Ding Y, Xu G, Yang M, Yao M, George F. Gao, Wang L, Zhang W & Rao Z*. 2003. Crystal structure of the ectodomain of human FcalphaRI. J Biol Chem., 278 (30): 27966-27970 (cover)

160. Ding Y, Xu M, I Ghosh, Chen Xi, S. Ferrandon, G. Lesage & Rao Z*. 2003. Crystal structure of a mini-intein reveals a conserved catalytic module involved in side chain cyclization of asparagine during protein splicing. J Biol Chem., 278(40): 39133 - 39142

161. Bell S.G, Chen X, Sowden R.J, Xu F, Williams J.N, Wong L* ＆ Rao Z*. 2003. Molecular Recognition in (+)-alpha-Pinene Oxidation by Cytochrome P450(cam). J Am Chem Soc., 125(3): 705-714

162. He H, Ding Y, Bartlam M, Sun F, Le Y, Qin X, Tang H, Zhang R, Joachimiak A, Liu J, Zhao N ＆ Rao Z*. 2003. Crystal Structure of Tabtoxin Resistance Protein Complexed with Acetyl Coenzyme A Reveals the Mechanism for β-Lactam Acetylation. J Mol Biol., 325(5): 1019-1030

163. Li T, Sun F, Ji X, Feng Y ＆ Rao Z*. 2003. Structure Based Hyperthermostability of Archaeal Histone HPhA from Pyrococcus horikoshii. J Mol Biol., 325: 1031-1037

164. Zhang H, Wang G, Ding Y, Wang Z, Barraclough R*, Rudland P.S., Fernig D.G. ＆ Rao Z*. 2003. The Crystal Structure at 2A Resolution of the Ca2+-binding Protein S100P. J Mol Biol.，325(4): 785-794

165. Zhang X, Roe SM, Hou Y, Bartlam M, Rao Z, Pearl LH & Danpure CJ. 2003. Crystal structure of alanine: glyoxylate aminotransferase and the relationship between genotype and enzymatic phenotype in primary hyperoxaluria type 1. J. Mol. Biol., 331:

643-652

166. Fry EE, Knowles NJ, Newman JW, Wilsden G, Rao Z, King AM & Stuart DI. 2003. Crystal structure of Swine vesicular disease virus and implications for host adaptation. J Virol., 77(9):5475-5486

167. Sun F, Li P, Ding Y, Wang L, M Bartlam, Shu C, Shen B, Jiang H, Li S*& Rao Z*. 2003. Design and Structure Based Study of New Potential FKBP12 Inhibitors. Biophys. J, 85 (5): 3194-3201

168. Wang G, Guo R, M Bartlam, Yang H, Xue H, Li Y, Huang L& Rao Z*. 2003. Crystal structure of a DNA Binding Protein from the Hyperthermophilic Euryarchaeon Methanococcus jannaschii. Protein Science, 12 : 2815-2822

169. Bell SG, Chen X, Xu F, Rao Z & Wong LL. 2003. Engineering substrate recognition in catalysis by cytochrome P450cam. Biochem Soc Trans，31(3):558-562

170. Guo Q, Zhou W, HM Too, Li J, Liu Y, M Bartlam, Dong Y, KB Wong, PC Shaw* & Rao Z*. 2003. Substrate binding and catalysis in trichosanthin occur in different sites as revealed by the complex structures of several E85 mutants. Protein Eng., 16(6):391-396

171. Ding Y, HM Too, Wang Z, Liu Y, M Bartlam, Dong Y, k Wong, PC Shaw ＆ Rao Z*. 2003. The structural basis of Trp192 and the C-terminal region in trichosanthin for activity and conformational stability. Protein Eng., 16 (5):351-356

172. Zhu J, Li P, Wu T, Gao F, Ding Y, Zhang C, Rao Z, Gao GF ＆ Tien P. 2003. Design and analysis of post-fusion 6-helix bundle of heptad repeat regions from Newcastle disease virus F protein. Protein Eng., 16(5): 373-379

173. Sun L, Li X, Dong Y, Yang M, Liu Y, Han X, Zhang X, Pang H & Rao Z*. 2003. Crystallization and preliminary crystallographic analysis of human serine dehydratase. Acta Cryst., D(59): 2297-2299

174. Li P, Ding Y, Wu B, Shu C, Shen B ＆ Rao Z*. 2003. Crystal Structure of the N-terminal domain of human FKBP52. Acta Cryst., D59 (1): 16-22

175. Yang M, Liu B, Zhang X, Zhou W, Gao F, Pang H, Miao S, Wang L ＆ Rao Z*. 2003. Crystallization and Preliminary Crystallographic Analysis of partial extracellular fragment of a sperm membrane protein YWK-II protein/APPH related to the Alzheimer βA4-amyloid precursor protein. Acta Cryst., D59 (1): 146-149

176. Yang M, Zhou W, Zhang X, Hu W, Gao F, Pang H, Miao S, Wang L ＆ Rao Z*. 2003. Crystallization and Preliminary Crystallographic Analysis of extracellular fragment X3 of YWK-II protein/APPH: A human sperm membrane protein related to the Alzheimer β A4-amyloid precursor protein. Acta Cryst., D59(3): 506-508

177. Zeng Q, Li X, M Bartlam, Wang G, Pang H * & Rao Z*. 2003. Purification, crystallization and preliminary X-ray analysis of human Pirin. Acta Cryst., D59(8): 1496-1498

178. Zhu J, Ding Y, Gao F, Wu T, Catherine W. H. Zhang, Tien P, Rao Z & G.F Gao*. 2003. Crystallization and preliminary X-ray crystallographic analysis of the trimer core from measles virus fusion protein. Acta Cryst., D59(3): 587-590

179. Li P, Zhu J, Wu B, Gao F, Tien P, Rao Z ＆ Gao GF *. 2003. Crystallization and preliminary X-ray diffraction analysis of post-fusion six-helix bundle core structure from Newcastle disease virus F protein. Acta Cryst., D59(7): 1296-1298

180. Yang M, Li S, Liang G, Sun L, Zhang X, Liu N, Pang H, Miao S, Wang L & Rao Z*. 2003. Crystallization and preliminary crystallographic analysis of RSB-66: A round spermatid specific new protein. Acta Cryst., D59(10): 1853-1855

181. Wu B, Li P, Shu C, Shen B & Rao Z*. 2003. Crystallization and preliminary crystallographic studies on the C-terminal Domain of human FKBP52. Acta Cryst., D(59): 2269-2271

182. Yang M, Xu G, Li S, Sun L, Shi N, Zeng W, Pang H, Zhang W & Rao Z*. 2003. Crystallization and Preliminary crystallographic analysis of the extracellular fragment of FcαRI/CD89. Acta Cryst., D(59): 2251-2253

183. Zhu J, Zhang C, Rao Z, Tien P ＆Gao GF. 2003. Biochemical and biophysical analysis of heptad repeat regions from the fusion protein of Menangle virus, a newly emergent paramyxovirus. Arch Virol., 148(7): 1301-1316

184. Li T, Yang W, Rao Z* ＆ Zhai Zh*. 2003. Crystallization of the N-Terminal Domain of DFF45: the Mutual Chaperone Mechanism is Challenged. Protein and Peptide Letters, 10(2): 221-225

185. Ding Y, Li XF, Sun F, Liu JY, Zhao NM ＆ Rao Z*. 2003. Site-directed Mutagenesis and Preliminary X-ray Crystallographic Studies of the Tabtoxin Resistance Protein. Protein and Peptide Letters, 10(3): 255-263

186. Ye S, Pang H, Gu YY, Hua J, Chen XG, Bao CD, Wang Y, Zhang W, Qian J, Tsao BP, Hahn BH, Chen SL, Rao Z & Shen N. 2003. Protein interaction for an interferon-inducible systemic lupus associated gene, IFIT1. Rheumatology (Oxford), 42(10): 1155-1163

187. Wang G, Yang H, & Rao Z*. 2003. Improvement on diffraction resolution of an archaeon DNA binding protein by gel medium. Progress in Biochemistry and Biophysics, 30(3): 471-473

188. 常咏，李雪梅，饶子和*. 2003. 关于小分子热休克蛋白Hsp16.3各功能区作用的初步研究. 自然科学进展.13(10): 1099-1103

189. Wang G, Gao R, Yang H, Cao S, Feng Y & Rao Z*. 2003. Archaeal acylamino acid releasing enzyme/lipase: Crystallization and preliminary crystallographic analysis in a new crystal form. Chinese Science Bulletin, 48(2): 154-156

190. Cheng M、Ruan G & Rao Z*. 2003. Phylogeny reconstruction based on protein phylogenetic profiles of organisms . Progress in Natural Science，2 (13): 109-113

191. Li P, Wang L, Wu B, Shu C, Nie A, Shen B , Li S & Rao Z*. 2003. Crystallization and preliminary X-ray diffraction analysis of FKBP12 complexed with a new neurotrophic ligand. Progress in Natural Science, 13(10): 765-767

192. Ye S, Pang H, Gu YY, Shen N, Chen SL, Chen XG, Hua J, Qian J & Rao Z. 2003. Using GST-tag to capture protein interaction of an interferon-inducible systemic lupus associated gene, IFIT1. Zhonghua Yi Xue Za Zhi, 83(9): 770-773

193. Ding Y, Jiang W, Zhang S, Mao X, Bartlam M, Zhao G & Rao Z*. 2003. Crystallographic Studies of Cephalosporin Acylase from Pseudomonas sp. Strain 130. Tsinghua Science and Technology, 8(4): 395-401

194. Lin W, Sun F & Rao Z*. 2003. A Statistical Analysis of Protein-Protein Interaction with Knowledge-Based Potential at Residue Level. Tsinghua Science and Technology, 8(4): 402-406

2002

195. Rao Z & Gao GF. 2002. Lipid-antigen presentation by CD1 is crystal clear. Trends in Immunology, 23(10): 473 （Review）

196. Gao GF*, Rao Z & Bell JI. 2002. Molecular coordination of alphabeta T-cell receptors and coreceptors CD8 and CD4 in their recognition of peptide-MHC ligands. Trends in Immunology, 23(8): 408-413 （Review）

197. Gao GF & Rao Z. 2002. Seeing the change: TCR binds pMHC with an ‘induced-fit’. Trends in Immunology, 23 (6): 281 （Review）

198. Chen XH, Christopher A, Jones JP, Bell SG, Guo Q, Xu F，Rao Z* & Wong LL*. 2002. Crystal structure of the F87W/Y96F/V247L mutant of cytochrome P450cam with 1,3,5-trichlorobenzene bound and further protein engineering for the oxidation of pentachlorobenzene and hexachlorobenzene. J. Biol. Chem., 277 (40): 37519-37526

199. Huang X, Zeng R, Ding X, Mao X, Ding Y, Rao Z, Xie Y, Jiang W & Zhao G. 2002. Affinity alkylation of the Trp-B4 residue of -subunit of the GL-7-ACA acylase of Pseudomonas sp. 130. J. Biol. Chem., 277(12): 10256-10264

200. Riffel N, Harlos K，Iourin O, Rao Z, Kingsman A, Stuart D &Fry E. 2002. Atomic Resolution Structure of Moloney Murine Leukemia Virus Matrix Protein and Its Relationship to Other Retroviral Matrix Proteins. Structure, 10(12): 1627-1636

201. Hatanaka H, Iourin O, Rao Z, Fry E, Kingsman A & Stuart DI. 2002. Structure of Equine Infectious Anemia Virus Matrix Protein, J Virol., 76 (4): 1876-1883

202. Yu M, Wang E, Liu YF, Cao DJ, Jin NY, Catherine W, Zhang H, Bartlam M, Rao Z, Tien P & Gao GF. 2002. Six-helix bundle assembly and characterization of heptad repeat regions from the F protein of Newcastle disease virus. J Gen Virol., 83: 623–629

203. Chen Y, Song G, Jiang F, Feng L, Zhang X, Ding Y, Bartlam M, Yang A, Ma X, Ye S, Liu Y, Tang H, Song H & Rao Z*. 2002. Crystal structure of a Staphylokinase variant :A model for reduced antigenicity. Eur. J. Biochem,, 269: 705-711

204. Jin J, Chen X, Zhou Y, Bartlam M, Guo Q, Liu Y, Sun Y, Gao Y, Ye S, Li G, Rao Z*, Qiang BQ & Yuan JG. 2002. Crystal structure of the catalytic domain of a human thioredoxin-like protein. Eur. J. Biochem., 269: 2060-2068

205. Meng SD, Song J, Rao Z, Tien P & Gao GF. 2002. Three-step purification of gp96 from human liver tumor tissues suitable for isolation of gp96-bound peptides. Journal of Immunological Methods, 264: 29-35

206. Jing F, Lin W & Rao Z. 2002. SOFTDOCK: understanding of molecular recognition through a systematic docking study. Protein Engineering, 15(4): 257-263

207. Zhang H, Wang Z, Ding Y, Wang G, Wang X, Bartlam M, Tang H, Liu Y, Jiang F, Barraclough R, Rudland P & Rao Z*. 2002. Crystallization and preliminary crystallographic analysis of a metastasis-inducing protein, human S100A4. Acta Cryst., D58 (21): 127-129

208. Li T, Ji X, Sun F, Gao R, Cao S, Feng Y & Rao Z*. 2002. Crystallization and preliminary X-ray analysis of recombinant histone HphA from the hyperthermophilic archaeon Pyrococcus horikoshii OT3. Acta Cryst. D58: 870-871

209. Lin W, Zhao Q, Bartlam M, Ding Y, Li D, Chen Y, Bao H, Xie Q & Rao Z*. 2002. Purification, crystallization and X-ray analysis of swine vesicular disease virus. Acta Cryst., D58(6): 1056-1058

210. Zhang H, Wang Z, Ding Y, Wang G, Wang X, Gao F, Tang H, Barraclough R, Rudland P & Rao Z*. 2002. Purification, Crystallization and preliminary X-ray diffrection sutides of a Ca2+binding protein, human S100P. Acta Cryst., D58: 694-696

211. Chen Y, Shao Y, Bartlam M, Li J, Jin L, Gao Y, Liu Y, Tang H, Zhen Y & Rao Z*. 2002. Crystallization and Preliminary X-ray Crystallographic Studies of A Macromolecular Antitumor Antibiotic,C1027. Acta Cryst. D58: 173-175

212. Chen X, Xu MQ, Ding Y, Ferrandon S & Rao Z*. 2002. Purification and Initial Crystallization studies of a DnaB intein from Synechocystis sp. PCC 6803. Acta Cryst., D58: 1201-1203

213. Chen X, Xu MQ, Ding Y, Ferrandon S & Rao Z*. 2002. Crystallographic study of a naturally occurring trans-splicing intein from Synechocystis sp. PCC 6803. Acta Cryst., D58: 1204-1206

214. Wang G, Gao R, Ding Y, Yang H, Cao S, Feng Y & Rao Z*. 2002. Crystallization and Preliminary Crystallographic Analysis of Acylamino Acid Releasing Enzyme from Hyperthermophilic Archaeon Aeropyrum pernix. Acta Cryst., D58: 1054-1055

215. Gao Y, Ding Y, Singh P & Rao Z*. 2002. Crystallization and preliminary crystallographic studies on the chromo shadow domain (CSD) of mouse heterochromatin protein M31. Acta Cryst., D58:1051-1053

216. Wang G, Guo R, Bartlam M, Xue H, Yang H, Liu Y, Huang L & Rao Z*. 2002. Expression, purification, crystallization and preliminary X-ray analysis of a DNA-binding protein from Methanococcus jannaschii. Acta Cryst., D58: 1240-1242

217. Li P, Shu C, Wu B, Ding Y, Shen B & Rao Z*. 2002. Crystallization and preliminary X-ray diffraction analysis of FKBP52 N-terminal domain. Acta Cryst., D58(12): 2168-2169

218. Shi N, Zhou W, Tang K, Gao Y, Jin J, Gao F, Peng X, Bartlam M, Qiang B, Yuan J & Rao Z*. 2002. Expression, crystallization and preliminary X-ray studies of the recombinant PTB domain of human dok-5 protein. Acta Cryst., D58(12): 2170-2172

219. Zhang S, Zhou W, Ding Y, He X, Zhang H, An J, Gao F, Heckmann K, Liang A & Rao Z*. 2002. Preliminary X-ray crystallographic analysis of ciliate Euplotes octocarinatus release factor eRF1a. Protein and Peptide Letters, 9 (1): 81-85

220. Li P, Wang L, Ding Y, Wu B, Shu C, Nie A, Li S, Shen B & Rao Z*. 2002. Crystallization and preliminary X-ray diffraction analysis of FKBP12 complexed with a novel neurotrophic ligand, Protein and Peptide Letters, 5 (9): 459-463

221. Li X, DingY, Too H, Wang Z, Liu Y, Dong Y, Shaw P & Rao Z*. 2002. Crystallization and Preliminary X-Ray crystallographic Studies of Trichosanthin Delta C7. Protein and Peptide Letters, 9(3): 269-273

222. Lin W, Sun F & Rao Z*. 2002. Tri-residue contact potential: a new knowledge-based energetic method*. Progress in Natural Science, 11(12): 826-840

2001

223. Wang ZL, Zhang HM, Ding Y, Wang GZ, Wang XD, Ye S, Bartlam M, Tang H, Liu YW, Jiang F, Barraclough R, Rudland PS & Rao Z*. 2001. Preliminary X-ray crystallographic analysis of a Ca2+-binding protein human S100A1. Acta Cryst., D57: 882-883

224. Jiang F & Rao Z*. 2001. A new implementation of the molecular replacement method using a six-dimensional Patterson vector search. J. Synch. Rad., 8: 1051-1053

225. Chen XH, Jin J, Guo Y, Sun YX, Tang H, Yuan JG, Qiang BQ & Rao Z*. 2001. Crystallization and preliminary X-ray analysis of a Trx domain of human thioredoxin-like protein. Acta Cryst.，D57: 1712-1714

226. He H, Ding Y, Cao Z, Bartlam M, Tang H, Jiang F, Liu Y, Liu JY, Zhao NM & Rao Z*. 2001. Crystallization and preliminary X-ray crystallographic analysis of native and selenomethionyl recombinant tabtoxin-resistance protein complexed with acetyl-Coenzyme A. Acta Cryst., D57: 1729-1731

227. Chen Y, An J, Song G, Feng L, Ding Y, Chang Y, Chen F, Liu B, He H, Tang H, Song H & Rao Z*. 2001. Crystallization and Preliminary X-Ray Crystallographic Studies of Staphylokinase Variant S41G. Protein and Peptide Letters, 8(6): 503-507

228. Chen Y, An J, Ding Y, Dai H, Mao Q, Feng L, Liu B, Chang Y, Chen F, He H, Tang H, Chang Z & Rao Z*. 2001. Preliminary X-ray Crystallographic Studies of the Mycobacterium Tuberculosis Hsp16.3 Molecular Chaperone. Protein and Peptide Letters, 8 (6): 499-502

229. Wang LW, Zhu L, Zhou JM & Rao Z*. 2001. Crystallization and preliminary X-ray crystallographic analysis of yeast prion protein Ure2q with shorted N-terminal. Chinese Science Bulletin, 46(12): 1012-1014

230. He HZ, Shao Y, Chen YH, Liu BB, Cao ZB, Jiang F, Liu YW, Tang H, Liu JY, Zhao NM & Rao Z*. 2001. Preparation of the selenomethionine derivative of tabtoxin resistance protein. Chinese Science Bulletin, 46(15): 1304-1307

231. Li YM，Rao Z & Tian P. 2001. Conformational change of glutatione S transferase by its co-expression with prion domain of yeast Ure2p. Progress in Natural Science, 11(10): 754-759

232. 陈微涛，王大伟，饶子和，田波. 2001. 二价铜离子对牛正常朊蛋白二级结构的影响. 自然科学进展，11(11): 1165-1169

233. Wang Y, Ye S, Ruan G, Bartlam M, Jiang F & Rao Z*. 2001. Computational Biology Study of S100 Family with suggestions for Crystallization. Tsinghua Science and Technology, 6(3): 248-252

2000 and earlier

234. 林巍，饶子和，梁国栋. 2000. 辛德毕斯病毒蛋白质结构与功能的研究进展. 病毒学报，4(16): 383-385

235. Wang DW, Yang HY，Rao Z & Tien P. 2000. High-level expression and secondary structure analysis of the bovine mature prion protein. Chinese Science Bulletin, 45(14): 1312-1315

236. 王大伟，王学，韩生成，田波，饶子和. 1998. 中国牛朊病毒基因的克隆和序列分析. 微生物学报, 38(6): 417-421

237. Nicolson D, Wong L & Rao Z. 1997. An Improved Procedure for the Preparation of X-ray diffraction Quality Crystals of Cytochrome P450(cam). Acta Cryst., D54: 470-472

238. Sharma A, Rao, Z, Fry E, Rowlands D & Stuart D. 1997. Specific Interactions Between Human Integrin аvβ3 and Chimerical Hepatitis B Virus Core Particles Bearing the Receptor-Binding Epitope of Foot-and Mouth Disease Virus. Virology, 239(1): 150-157

239. Rao Z, Handford P, Mayhew M, Knott V, Brownlee G & Stuart D. 1996. SIV matrix antigen, G2A mutant. Macromolecular Structures，published by Current Biology Ltd. Part 1: 252

240. Rao Z, Handford P, Mayhew M, Knott V, Brownlee G & Stuart D, 1996. Factor IX, Ca2＋-binding EGF-like domain. Macromolecular Structures, published by Current Biology Ltd. Part 2: 366

241. Karlsen S, Hough E, Rao Z & Isaacs N. 1996. Structure of a Bulgecin-Inhibited g-Type Lysozyme from the Egg White of the Australian Black Swan. A Comparison of the binding of Bulgecin to Three Muramidases. Acta Cryst., D52: 105-114

242. Rao Z, Belyaev A, Fry E, Jones I, Roy P & Stuart D. 1995. Crystal Structure of SIV Matrix Antigen and its Implications for Virus Assembly. Nature，378(6558): 743-747

243. Rao Z, Handford P, Mayhew M, Knott V, Brownlee G & Stuart D. 1995. The Structure of a Calcium Binding Epidermal Growth Factor-like Domain - its Role in Protein-Protein Interactions. Cell, 82(1): 131-141

244. Rao Z, Handford P, Mayhew M, Knott V, Brownlee G & Stuart D. 1995. Crystallization of a Calcium Binding EGF-like Domain. Acta Cryst, D51: 402-403

245. Handford P, Downing A, Rao Z, Hewett D, Sykes B & Kielty C. 1995. The Calcium Binding Properties and Molecular Organization of Epidermal Growth Factor-like Domains in Human Fibrillin-1. J. Biol Chem.，270(12): 6751-6756

246. Rao Z, Esnouf R., Isaacs N & Stuart D. 1995. A Strategy for Rapid and Effective Refinement Applied to Black Swan Lysozyme. Acta Cryst, D51: 331-336

247. Rees DJG, Grant RP, Rao Z & Stuart DI.. 1994. The N-Terminal Domain of Talin-initial Structural and Functional-studies. Journal of Cellular Biochemistry. 18: 262-262

248. Rao Z.“Structure of Black Swan Goose-type Lysozyme”，Ph.D. Thesis，University of Melbourne, 1989

249. 梁栋材，戴金璧,常文瑞， D. Stuart R. Todd, 万柱礼，饶子和，楼美珍，游俊明，张季平，谢殿霖. 1987. 胰岛素及其类似物的晶体学研究. 生物化学与生物物理学报，19 (1) : 83-92

250. Wei H, Rao Z, Dai J & Liang D. 1986. Crystal growth and preliminary crystallographic observation of (Leu)B1 insulin, Kexue Tongbao, 22(31): 1574-1576

251. 滕脉坤、饶子和、孔德云、刘星堦. 1985. 丹参缩酮内酯（丹参晶IX）的具体及分子结构研究. 中国科学技术大学学报 1 (15): 92-99

252. 饶子和，戴金璧，梁栋材.1985. 旋转函数在B0-(L-Met)-胰岛素晶体结构分析中的应用.生物化学与生物物理学报，3(17):373-381

253. 饶子和，戴金璧，梁栋材. 1984. 两种新晶型的去五肽(B26-30)胰岛素晶体学研究.科学通报，23:1454-1457

254. 孔德云、刘星堦、滕脉坤*、饶子和*. 1985. 丹参中丹参螺旋缩酮内酯的结构. 药学学报. 20(10): 747-751

255. Dai J, Wan Z, Rao Z, Liang D, Fang Z, Luo Y & Long K. 1985. Molecular structure and absolute configuration of the diterpene lactone praelolide, Scientia Sinica, 11(28B): 1132-1142

256. Rao Z, Dai J, Wan Z, Liang D & Wang D. 1983. Crystal and molecular structure of dehydrocrydaline chloride. Scientia Sinica, 11(26B): 1155-1165

257. 万柱礼，乔国正，饶子和，梁栋材. 1983. 延胡索乙素的晶体及分子结构. 结构化学，2(2):95-100

258. 饶子和，万柱礼，梁栋材. 1982. 钩吻素溴氢酸盐的晶体结构及其分子的绝对构型.物理学报，31 (4): 547-553

259. 万柱礼，饶子和，梁栋材，姚心侃，阎世平，王耕霖. 1982. 硝酸镧与大环聚醚1，8-萘并-16-冠-5络合物的分子和晶体的结构.化学学报, 40 (12):1087-1093

260. Rao Z, M.Sc. Thesis: “An Application of Molecular Replacement to the Determination of the Crystal Structure of (L-met) - Insulin” USTC, (1982)

261. Wang G, Yan S, Li X, Yao X, Wan Z, Rao Z & Liang D. 1982. Syntheses and properties of eleven-coordinated complexes formed from lanthanide nitrates and 1,8-naphtho-16-crown-5.Scientia Sinica, 9(25B): 916-923

262. 李家瑶，宋时英，李军，王家槐，饶子和. 1980. 用单对同晶加常反射法测定去B链羧端五肽（B26-B30）胰岛素晶体结构4Å分辨率的初步结果. 科学通报, 4: 43-45

263. 王家槐，李家瑶，饶子和，桂璐璐，柚美珍，游俊民，宋时英. 1980. 去B链羧端五肽（B26-B30）胰岛素晶体结构的原子衍生物分析. 科学通报, 8: 369-371

264. Rao Z.“Studies of the heavy atom derivatives of despentapeptide (B26-0)-Insulin” Thesis: University of Science and Technology of China (USTC) (1977)

注：*为通讯作者(* Corresponding author)